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Truth serum
A "truth serum" is a colloquial name for any of a range of psychoactive medications used to obtain information from subjects who are unable or unwilling to provide it otherwise. Any information from the truth serum report is corroborated by further investigation. They have been used in the course of investigating civil and criminal cases, and for the evaluation of psychotic patients in the practice of psychiatry.〔Naples M, Hackett TP: The amytal interview: history and current uses. ''Psychosomatics01'' 1978; 19: 98–105.〕 That application was first documented by Dr. William Bleckwenn in 1930,〔Bleckwenn WJ: Sodium amytal in certain nervous and mental conditions. ''Wis Med'' J 1930; 29: 693–696.〕 and it still has selected uses today. In the latter context, the controlled administration of intravenous hypnotic medications is called "narcosynthesis" or "narcoanalysis." It may be used to procure diagnostically – or therapeutically – vital information, and to provide patients with a functional respite from catatonia or mania.〔Tollefson GD: The amobarbital interview in the differential diagnosis of catatonia. ''Psychosomatics'' 1982; 23: 437–438.〕〔Bleckwenn WJ: Production of sleep and rest in psychotic cases. ''Arch Neurol Psychiatry'' 1930; 24: 365–375.〕 == Active chemical substances ==
Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates including sodium thiopental (commonly known by the brand name Sodium Pentothal) and amobarbital (formerly known as sodium amytal).〔Anonymous: Barbiturates. ''http://www.surgeryencyclopedia.com/A-Ce/Barbiturates.html'', Accessed 9-21-2009.〕
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